After using the Express command line generation untility, you get a very basic layout.jade. Here's the standard modifications I make for use with BootstrapCDN.
!!! 5 html head meta(charset='utf-8') meta(name='viewport', content='width=device-width, initial-scale=1.0') meta(name='description', content='') meta(name='author', content='') title= title link(rel='stylesheet', href='//netdna.bootstrapcdn.com/bootstrap/3.0.0/css/bootstrap.min.css') // if lt IE 9 script(src='//cdnjs.cloudflare.com/ajax/libs/html5shiv/3.6.2/html5shiv.min.js') script(src='//cdnjs.cloudflare.com/ajax/libs/respond.js/1.3.0/respond.min.js') body .container block content script(src='//netdna.bootstrapcdn.com/bootstrap/3.0.0/js/bootstrap.min.js', async=true)